Can the sugar substitute Splenda/sucralose make your glucose count go up? How does this compare to Nutrasweet/aspartame and Sweet n Low/saccharin?

The Food and Drug Administration as approved five artificial sweeteners: neotame, sucralose (Splenda), acesulfame-K (Sweet One), aspartame (Nutrasweet) and saccharin (Sweet & Low). Artificial sweeteners can help to satisfy cravings for sugary foods without as many calories or as big of an impact on blood sugar levels. While the artificial sweetener itself will not likely affect your blood glucose levels, foods made sweeteners also have other ingredients that may affect blood sugar. Just because a product says “sugar free” does not mean that it is carbohydrate free and will still contain calories. For example, a piece of “sugar free” pie sweetened with sucralose will contain less sugar than regular pie, but it is still made with flour and the flour will affect blood sugar. A container of yogurt sweetened with aspartame still contains lactose, which is a milk sugar and can affect blood sugar levels.

The main difference between the artificial sweeteners is the level of sweetness. A good table to compare the sweetness levels of the sweeteners can be found here

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